List of Publications

48. “Palladium-Catalyzed C(sp2)−N Bond Cross-Coupling with Triaryl Phosphates” Chen, Z.; Chen, X.; So, C. M.* J. Org. Chem. 2019, 84, 6366-6376.

47. “Exploration of Aryl Phosphates in Palladium-Catalyzed Mono-α-arylation of Aryl and Heteroaryl Ketones” Chen, X.; Chen, Z.; So, C. M.* J. Org. Chem. 2019, 84, 6337-6346.

46. “Synthesis of Flavone Derivatives through Versatile Palladium-Catalyzed Cross-Coupling Reactions of Tosyloxy- and Mesyloxyflavones” Yuen, O. Y.; Pang, W. H.; Chen, X.; Chen, Z.; Kwong, F. Y.; So, C. M.* Synlett 2019, 30, 731-737.https://www.thieme-connect.de/media/synlett/201906/i_u0040_ga_10-1055_s-0037-1611742.gif

45. “Palladium-Catalyzed N-Arylation of Sulfoximines with Aryl Sulfonates” Yang, Q.; Choy, P. Y.; Zhao, Q.; Leung, M. P.; Chan, H. S.; So, C. M.; Wong, W. –T.; Kwong, F. Y. J. Org. Chem. 2018, 83, 11369-11376.

44. “A General Palladium–Phosphine Complex To Explore Aryl Tosylates in the N‐Arylation of Amines: Scope and Limitations” Choy, P. Y.; Chung, K. H.; Yang, Q.; So, C. M.*; Sun, R. W. –Y.; Kwong, F. Y. Chem. Asian. J. 2018, 13, 2465-2474.

43. “Palladium-Catalyzed Direct Arylation of Polyfluoroarenes for Accessing Tetra-ortho-Substituted Biaryls: Buchwald-type Ligand Having Complementary −PPh2 Moiety Exhibits Better Efficiency” Yuen, O. Y.; Leung, M. P.; So, C. M.*; Sun, R. W. –Y.; Kwong, F. Y. J. Org. Chem. 2018, 83, 9008-9017.

42. “Bulky Phosphane Ligand for Monoselective Ruthenium-Catalyzed, Directed o-C–H Arylation with Challenging Aryl Chlorides” Lu, Y. G.; Wang, Z. Y.; Zou, Y. L.; So, C. M.; Kwong, F. Y.*; Qin, H. L.; Kantchev, E. A.* Synlett 2017, 28, 499-503. (chosen as Cover)

https://www.thieme-connect.de/media/synlett/201704/i_w0553_ga_10-1055_s-0036-1588635.gif

41. “Catalytic Direct C2-Alkenylation of Oxazoles at Parts per Million Levels of Palladium/PhMezole-Phos Complex” Fu, W. C.; Wu, Y.; So, C. M.; Wong, S. M.; Lei, A.; Kwong, F. Y. Org. Lett. 2016, 18, 5300-5303.

40. “Exploiting Aryl Mesylates and Tosylates in Catalytic Mono-α-Arylation of Aryl- and Heteroarylketones” Fu, W. C.; So, C. M.; Yuen, O. Y.; Lee, I.; Kwong, F. Y. Org. Lett. 2016, 18, 1872-1875.

39. “A General Palladium-Catalyzed Hiyama Cross-Coupling Reaction of Aryl and Heteroaryl Chlorides” Yuen, O. Y.; So, C. M.*; Man, H. W.; Kwong, F. Y. Chem. Eur. J. 2016, 22, 6471-6476. (chosen as Hot Paper & Inside Back Cover & Highlighted in the Chemistry Views)

38. “Open-Air Oxidative Mizoroki-Heck Reaction of Arylsulfonyl Hydrazides with Alkenes” Yuen, O. Y.; So, C. M.*, Kwong, F. Y. RSC Adv. 2016, 6, 27584-27589.Graphical abstract: Open-air oxidative Mizoroki–Heck reaction of arylsulfonyl hydrazides with alkenes

37. “Preparation of 2-(2-(dicyclohexylphosphino)phenyl)-1-methyl-1H-indole (CM-phos)” Wong, S. M.; Yuen, O. Y.; Choy, P. Y.; So, C. M.*; Kwong, F. Y. Org. Synth. 2016, 93, 14-28.

Reaction scheme

36. “Palladium-catalyzed Buchwald-Hartwig Amination and Suzuki-Miyaura Cross-coupling Reaction of Aryl Mesylates” Wong, S. M.; Choy, P. Y.; Yuen, O. Y.; So, C. M.*; Kwong, F. Y. Organic Syntheses 2015, 92, 195-212.

Reaction scheme

35. “Palladium-Catalyzed Phosphorylation of Aryl Mesylates and Tosylates” Fu, W. C.; So, C. M.; Kwong, F. Y. Org. Lett. 2015, 17, 5906-5909.

34. “Design of an Indolylphosphine Ligand for Reductive Elimination-Demanding Monoarylation of Acetone Using Aryl Chlorides” Fu, W. C.; So, C. M.*; Chow, W. K.; Yuen, O. Y.; Kwong, F. Y. Org. Lett. 2015, 17, 4612-4615.

33. “A General Direct Arylation of Polyfluoroarenes with Heteroaryl and Aryl Chlorides Catalyzed by Palladium Indolylphosphine Complexes” Yuen, O. Y.; Charoensak, M.; So, C. M.; Kuhakarn, C.; Kwong, F. Y.* Chem. Asian. J. 2015, 10, 857-861.

32. “Rhodium/Chiral Diene-Catalyzed Asymmetric 1,4-Addition of Arylboronic Acids to Chromones: A Highly Enantioselective Pathway for Accessing Chiral Flavanones” He, Q.; So, C. M.; Bian, Z.; Hayashi, T.; Wang, J.* Chem. Asian. J. 2015, 10, 540-543.

31. “A Chiral Bicyclo[2.2.2]octa-2,5-diene Ligand Substituted with the Ferrocenyl Group and Its Use for Rhodium-Catalyzed Asymmetric 1,4-Addition Reactions” Zhou, B.; So, C. M.; Lu, Y.*; Hayashi, T.* Org. Chem. Front. 2015, 2, 127-132.

Graphical abstract: A chiral bicyclo[2.2.2]octa-2,5-diene ligand substituted with the ferrocenyl group and its use for rhodium-catalyzed asymmetric 1,4-addition reactions

30. “Regioselective Direct C-3 Arylation of Imidazo[1,2‑a]pyridines with Aryl Tosylates and Mesylates Promoted by Palladium−Phosphine Complexes” Choy, P. Y.; Luk, K. C.; Wu, Y.; So, C. M.; Wang, L.*; Kwong, F. Y.* J. Org. Chem. 2015, 80, 1457-1463.

29. “A General Suzuki-Miyaura Coupling of Aryl Chlorides with Potassium Aryltrifluoroborates in Water Catalyzed by an Efficient CPCY Phendole-phos-Palladium Complex” Yuen, O. Y.; Wong, S. M.; Chan, K. F.; So, C. M.*; Kwong, F. Y. Synthesis 201446, 2826-2832.

https://www.thieme-connect.de/media/synthesis/201420/i_h0287_ga_10-1055_s-0033-1338660.jpg

28. “Palladium-Catalyzed Reductive Cleavage of Tosylated Arenes Using Isopropanol as the Mild Reducing Agent” Chow, W. K.; So, C. M.; Lau, C. P.; Kwong, F. Y. Org. Chem. Front. 20141, 464-467.

Graphical abstract: Palladium-catalyzed reductive cleavage of tosylated arenes using isopropanol as the mild reducing agent

27. “Rhodium-Catalyzed Asymmetric Hydroarylation of 3-Pyrrolines Giving 3-Arylpyrrolidines: Protonation as a Key Step” So, C. M.; Satoshi, K.; Hayashi, T.* J. Am. Chem. Soc. 2013, 135, 10990-10993.

26. “A Decade Advancement of Transition Metal-Catalyzed Borylation of Aryl Halides and Sulfonates” Chow, W. K.; Yuen, O. Y.; Choy, P. Y.; So, C. M.; Lau, C. P.; Wong, W. T.; Kwong, F. Y. RSC Adv. 20133, 12518-12539.

Graphical abstract: A decade advancement of transition metal-catalyzed borylation of aryl halides and sulfonates

25. “Direct Oxidative C-H Arylation of Benzoxazoles with Arylsulfonyl Hydrazides Promoted by Palladium Complexes” Yuen, O. Y.; So, C. M.; Wong, W. T.; Kwong, F. Y. Synlett 2012, 23, 2714-2718.

https://www.thieme-connect.de/media/synlett/201218/w0702_ga.gif

24. “An Efficient Class of P,N-Type "PhMezole-phos" Ligands: Applications in Palladium-Catalyzed Suzuki Coupling of Aryl Chlorides” Wong, S. M.; So, C. M.*; Chung, K. H.; Lau, C. P.; Kwong, F. Y. Eur. J. Org. Chem. 201222, 4172-4177.

23. “P,N-Type Benzimidazolyl Phosphine Ligands for the Palladium-Catalyzed Suzuki Coupling of Potassium Aryltrifluoroborates and Aryl Chlorides” Wong, S. M.; So, C. M.*; Chung, K. Ho; L., C. H.; Lau, C. P.; Kwong, F. Y. T. Lett. 201253, 3754-3757.

22. “Buchwald-Hartwig Amination of Aryl Chlorides Catalyzed by Easily Accessible Benzimidazolyl Phosphine-Pd Complexes” Chung, K. H.; So, C. M.*; Wong, S. M.; Luk, C. H.; Zhou, Z.; Lau, C. P.; Kwong, F. Y. Synlett 201223, 1181-1186.https://www.thieme-connect.de/media/synlett/201208/w812_ga.gif

21. “The Recent Development of Phosphine Ligands Derived from 2-Phosphino-Substituted Heterocycles and Their Applications in Palladium-Catalyzed Cross-Coupling Reactions” Wong, S. M.; So, C. M.; Kwong, F. Y. Synlett 201223, 1132-1153.

https://www.thieme-connect.de/media/synlett/201208/a621_ga.jpg

20. “Carbon-Boron Bond Cross-Coupling Reaction Catalyzed by –PPh2 Containing Palladium-Indolylphosphine Complexes” Chow, W. K.; Yuen, O. Y.; So, C. M.; Wong, W. T.; Kwong, F. Y. J. Org. Chem. 2012, 77, 3543-3548.

19. “Palladium-Catalyzed Direct Arylation of Polyfluoroarenes with Aryl Tosylates and Mesylates” Lee, D. S.; Choy, P. Y.; So, C. M.; Wang, J.; Lau, C. P.; Kwong, F. Y. RSC Adv. 20122, 9179-9182.

Graphical abstract: Palladium-catalyzed direct arylation of polyfluoroarenes with aryl tosylates and mesylates

18. “An Efficient Palladium–Benzimidazolyl Phosphine Complex for the Suzuki–Miyaura Coupling of Aryl Mesylates: Facile Ligand Synthesis and Metal Complex Characterization” Chung, K. H.; So, C. M.*; Wong, S. M.; Luk, C. H.; Zhou, Z.; Lau, C. P.; Kwong F. Y. Chem. Commun. 2012, 48, 1967-1969.

Graphical abstract: An efficient palladium–benzimidazolyl phosphine complex for the Suzuki–Miyaura coupling of aryl mesylates: facile ligand synthesis and metal complex characterization

17. “Palladium-Catalyzed Borylation of Aryl Mesylates and Tosylates and Their Applications in One-Pot Sequential Suzuki-Miyaura Biaryl Synthesis” Chow, W. K.; So, C. M.; Lau, C. P.; Kwong, F. Y. Chem. Eur. J. 2011, 17, 6913-6917.

16. “A Mild and Efficient Palladium-Catalyzed Cyanation of Aryl Chlorides with K4[Fe(CN)6]” Yeung, P. Y.; So, C. M.; Lau, C. P.; Kwong, F. Y. Org. Lett. 2011, 13, 648-651.

15. “Hydro(trispyrazolyl)borato-Ruthenium(II) Diphosphinoamino Complex- Catalyzed Addition of β-Diketones to 1-Alkynes and Anti-Markovnikov Addition of Secondary Amines to Aromatic 1-Alkynes” Cheung, H. W.; So, C. M.; Pun, K. H.; Zhou, Z.; Lau, C. P. Adv. Synth. Catal. 2011, 353, 411-425.

14. “Palladium-Catalyzed Direct Arylations of Heteroarenes with Aryl Mesylates” So, C. M.; Lau, C. P.; Kwong, F. Y. Chem. Eur. J. 2011, 17, 761-765.

13. “Palladium-Catalyzed Cross-Coupling Reactions of Aryl Mesylates” So, C. M.; Kwong, F. Y. Chem. Soc. Rev.  2011, 40, 4963-4972.

Graphical abstract: Palladium-catalyzed cross-coupling reactions of aryl mesylates

12. “A Versatile Palladium Catalyst System for Suzuki–Miyaura Coupling of Alkenyl Tosylates and Mesylates” Wong, P. Y.; Chow, W. K.; Chung, K. H.; So, C. M.; Lau. C. P.; Kwong, F. Y. Chem. Commun. 2011, 47, 8328–8330.

Graphical abstract: A versatile palladium catalyst system for Suzuki–Miyaura coupling of alkenyl tosylates and mesylates

11. “Palladium-Catalyzed Sonogashira Coupling of Aryl Mesylates and Tosylates” Choy, P. Y.; Chow, W. K.; So, C. M.; Lau, C. P.; Kwong, F. Y. Chem. Eur. J. 2010, 16, 9982-9985.

10. “A General Palladium Catalyst System for Suzuki-Miyaura Coupling of Potassium Aryltrifluoroborates and Aryl Mesylates” Chow, W. K.; So, C. M.; Lau, C. P.; Kwong, F. Y. J. Org. Chem. 2010, 75, 5109-5112.

9. “Remarkably Effective Phosphanes Simply with a PPh2 Moiety: Application to Pd-Catalysed Cross-Coupling Reactions for Tetra-ortho-substituted biaryl Syntheses” So, C. M.; Chow, W. K.; Choy, P. Y.; Lau, C. P.; Kwong, F. Y. Chem. Eur. J. 2010, 16, 7996-8001.

8. “A Mild and Efficient Palladium-Catalyzed Cyanation of Aryl Mesylates in Water or tBuOH/Water” Yeung, P. Y.; So, C. M.; Lau, C. P.; Kwong, F. Y. Angew. Chem. Int. Ed. 2010, 122, 9102-9106. (chosen as Hot Paper)

7. “Palladium-Indolylphosphine-Catalyzed Hiyama Cross-Coupling of Aryl Mesylates” So, C. M.; Lee, H.W.; Lau, C. P.; Kwong, F. Y. Org. Lett. 2009, 11, 317-320.

6. “Palladium-Catalyzed Cross-Coupling of Aryl Halides Using Organotitanium Nucleophiles” Lee, H. W.; Lam, F. L.; So, C. M.; Lau, C. P.; Chan, A. S. C.; Kwong, F. Y. Angew. Chem. Int. Ed. 2009, 121, 7572-7575.

5. “A New Family of Tunable Indolylphosphine Ligands by One-Pot Assembly and Their Applications in Suzuki-Miyaura Coupling of Aryl Chlorides” So, C. M.; Yeung, C. C.; Lau, C. P.; Kwong, F. Y. J. Org. Chem. 2008, 73, 7803-7806.

4. “Suzuki-Miyaura Coupling of Aryl Tosylates Catalyzed by an Array of Indolyl Phosphine-Palladium Catalysts” So, C. M.; Lau, C. P.; Chan, A. S. C.; Kwong, F. Y. J. Org. Chem. 2008, 73, 7731-7734.

3. “A General Palladium-Catalyzed Suzuki–Miyaura Coupling of Aryl Mesylates” So, C. M.; Lau, C. P.; Kwong, F. Y. Angew. Chem. Int. Ed. 2008, 47, 8059-8063.

2. “Palladium-Catalyzed Amination of Aryl Mesylates” So, C. M.; Zhou, Z.; Lau, C. P.; Kwong, F. Y. Angew. Chem. Int. Ed. 2008, 47, 6402-6406.

1.“Easily Accessible and Highly Tunable Indolyl Phosphine Ligands for Suzuki-Miyaura Coupling of Aryl Chlorides” So, C. M.; Lau, C. P.; Kwong, F. Y. Org. Lett. 2007, 9, 2795-2798.

 

Book Chapter:

Wong, S. M.; So, C. M.*; Kwong, F. Y. Ligand-Enabled Palladium-Catalyzed C-N and C-O Bond Formations from Aryl Halides, Tosylates and Mesylates. In Applied Homogeneous Catalysis with Organometallic Compounds; Cornils, B., Herrmann, W. A., Beller, M., Paciello, R., Eds.; Wiley-VCH: Weinheim, 2017; pp 435-464.

Patents:

1. Kwong, F. Y.; So, C. M. Ligands for Transition-Metals and Methods of Use. US Patent 8212056-B2.

2. 邝福儿, 周永健, 苏秋铭, 蔡珮盈 "高位阻芳基硼酸酯类化合物的制备方法"

3. 邝福儿, 蔡珮盈, 苏秋铭, 原安莹 "(2﹣二取代膦苯基)-1-烷基-吲哚膦配体及其合成方法和应用"